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Top 5 Supplements for Anxiety and Depression

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For Consumers Still Affected by Unsettling Economy

Since 2013, when consumers experienced repercussions from the worst recession in 70 years, including soaring unemployment rates financial stress, treatment for Anxiety and Depression have risen. Financial stress takes its toll on our nervous system, and perhaps not surprisingly, even on brain functions.

Anxiety and depression seem to be a little more common in terms of what I’ve seen in the past six to 12 months. It’s easy enough to equate it with what’s happening in the economy,” said Naturopathic physician Dr. Michael Smith, ND, at Carolinas Natural Health Center in Matthew, N.C.

Pharmaceutical Treatment for Depression Not Effective

Statistical data from the National Institute of Health shows about 14.8 million Americans suffer from Major Depressive Disorder and approximately 40 million adult Americans personally report related anxiety disorders every year.

Mintel, a Chicago-based research company, reported $22.7 million in sales of prescription depression medication and anxiety-related drugs. After examining 240 patients suffering from severe to moderate anxiety depression, researchers concluded that over 50% of the patients didn’t respond to conventional anti-depression medications. Another study at Mintel revealed that 38 percent of patients who suffered from common anxiety problems adopted treatment other than prescription medications.

Supplements Help Depressive Symptoms

No wonder the high upswing in sales of the many natural anti-depression supplements that fight depression and anxiety. Here we’ll examine five top-notch natural anti-anxiety and depression supplements:


Fish oil can be a good anti-depressant since it boosts maximum brain chemistry through omega-3 fatty acids. A 2009 research report revealed that higher intake of omega-3s and oily fish may decrease the depressions women suffer by about 30%. Omega-3 is most available in cold-water fish; and that amount of omega-6 fatty acids (although good) in foods like canola oil and nuts doesn’t supersede omega-3s.

Tip: If you are already on an SSRI, experts recommend consulting with a physician before adding supplements like B6 and B3 that manipulate serotonin.


Vitamin B6 and B3 (Niacinamide) makes your body conserve the amino acid tryptophan and converts as much tryptophan as possible into serotonin (mood enhancers), responsible for brain natural-neurotransmitters that help transmit signals between cells. Serotonin in antidepressants focus on one neurotransmitter, unlike Vitamin B6 and B3. Vitamin B12 with folic acid can be helpful if condition persists.


This amino acid 5-HTP also helps boost serotonin levels for people that selective serotonin reuptake inhibitors (SSRIs) like Prozac couldn’t help. SSRIs stores serotonin which is not fancied by experts. However, 5-HTP is converted into serotonin in the body. Best is taking fat-soluble 5-HTP version that comes in a spray and is largely consumed before reaching the digestive system.


This amino acid byproduct of green tea has proven to spark the release of gamma-aminobutyric acid (GABA) in the brain. The spark triggers activation of key calming neurotransmitters, causing relaxation and alleviating anxiety. Theanine is best for the body since the body hardly absorbs synthesized GABA. It is best taken under 600mg, unless on expert supervision.


Vitamin D supplements boost healthy teeth, bones, encouraging calcium absorption and fighting depression, as experts believe it possibly improves neurotransmitter functions. A blood test ensuring a patients’ serum levels are normal between 50 -100 nanograms per millileter and blood test follow-up three months after taking Vitamin D supplements is recommended.

Help for Treatment-Resistant Depression

These supplements may help mild symptoms. If you suffer increasing, recurrent, or treatment-resistant depression, consider alternatives to antidepressant medications.

TMS (Transcranial Magnetic Stimulation) is a new therapy that involves no drugs and is proven safe and effective – for treatment-resistant depression! TMS is free of the negative side effects often associated with taking antidepressants.

Top 5 Supplements for Anxiety and Depression

Dr. Scott West

About Nashville NeuroCare Therapy: In April of 2010, Dr. West brought the technology of NeuroStar TMS to Nashville, becoming the first physician in Tennessee to offer the option of Transcranial Magnetic Stimulation (TMS) for patients whose severe depression has not responded to a course of antidepressant medication or treatment for depression. The team at Nashville NeuroCare Therapy offers the most experience in the Tennessee-area. We have treated 550+ patients across the U.S. and administered 16,000+ TMS treatments, plus we maintain some of the highest percentages of positive patient responses and remission rates in the industry.

At Nashville NeuroCare Therapy, we deliver personalized therapy, specializing in TMS Therapy and Neurofeedback. We provide safe and well-researched therapies for depression, ADHD and sleep problems—all without the need for medication.

For more information on our therapies for Depression, ADHD and Sleep Problems, please contact us at (615) 465-4875 or or [email protected] or visit our website

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APA Reference
West, W. (2017). Top 5 Supplements for Anxiety and Depression. Psych Central. Retrieved on July 11, 2020, from


Last updated: 2 Aug 2017
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