Archives for March, 2012

Addiction

Inconvenient Truths

Next month I will be presenting a paper at the annual meeting of ASAM, the American Society of Addiction Medicine.  The paper discusses a new method for treating chronic pain, using a combination of buprenorphine and opioid agonists.  In my experience, the combination works very well, providing excellent analgesia and at the same time reducing—even eliminating-- the euphoria from opioids.

Ten years ago, I would have really been onto something. Back then there were calls...
Continue Reading

Addiction

Ceilings Revisited

A question was asked about the last post that warrants top billing:

"Buprenorphine acts similar to opioid agonists in lower doses, with the same addictive potential as oxycodone or heroin. In higher doses—doses above 8 mg or 8000 micrograms per day—the ‘ceiling effect' eliminates interest and cravings for the drug.”

I’m not sure I followed this. Can you explain more? What would you think about someone who is taking 1-2mg of Suboxone twice a day without...
Continue Reading