Archives for Lithium

Antidepressant

Reducing the Risk of Triggering Mania with the Use of Antidepressants in Bipolar Disorder

A recent article in the American Journal of Psychiatry sheds light on the vexing challenge of treating depression in individuals who have an underlying bipolar disorder: For many people with bipolar disorder, depression occurs more frequently and damages function more severely than mania, but treating bipolar depression with antidepressants carries the risk of triggering manic symptoms.
Continue Reading

Bipolar Medication

Taking an Anti-Inflammatory (NSAID)? Check Your Lithium Levels

My wife is seeing a psychiatrist who prescribed lithium for her bipolar disorder. Recently, she visited another doctor, who prescribed Mobic (meloxicam), a nonsteroidal anti-inflammatory drug (NSAID), for pain and swelling in her knee. A couple weeks later, we spent the afternoon in the emergency room, where my wife was treated for lithium toxicity and had her lithium blood level checked.
Continue Reading

Bipolar Medication

Ebselen May Work Like Lithium with Fewer Serious Side Effects

According to a recent study published in the journal Nature Communications entitled "A safe lithium mimetic for bipolar disorder," British researchers are exploring a medication called ebselen as a possible treatment for bipolar disorder in humans. Originally developed to treat stroke, ebselen may be as effective as lithium in treating bipolar mania but carry fewer and less serious side effects than lithium.

As the article points out,
Lithium is the most effective mood stabilizer...
Continue Reading

Bipolar Medication

Combatting Lithium Joint Pain and Headache Side Effects

Kim


Is there a way to combat the headaches and joint pains when taking the lithium?

Dr. Fink


Hi, Kim. Good question. Most importantly discuss these side effects with your doctor immediately. Your doctor may want to run a blood test to determine your lithium level and make sure your lithium level is not toxic. Headaches can indicate toxicity. Headaches may also be a sign of dehydration, which can occur with lithium, so keeping...
Continue Reading

Bipolar Medication

Lithium Increased Brain Volume in Patients with Bipolar Disorder

In an article published in this month's Biological Psychiatry entitled "Structural Magnetic Resonance Imaging in Bipolar Disorder: An International Collaborative Mega-Analysis of Individual Adult Patient Data" (Hallahan et al.), researchers pulled together a large number of magnetic resonance imaging studies to compare the brains of people with bipolar disorder to those of healthy control subjects. Their goal was to make sense of some of the conflicting data that had...
Continue Reading

12