For years, researchers and health policy experts have been charging that psychiatric medications aren’t adequately tested in children – and a new study gives some powerful ammunition to that critique.
The study, from Pediatrics, looked at clinical drug trials between 2006 and 2011, involving five conditions that cause the greatest “disease burden” for children, as measured by a rating that counts the total years of healthy life lost to disability.
In high-income countries like the United States, three of the five conditions with the highest disease burden among kids were psychiatric disorders: depression, bipolar disorder and schizophrenia.
But of the drug studies to treat those conditions, disproportionately few involved children.
The lack of trials is troubling because children and adults don’t necessarily respond to medication in the same way. With psychiatric drugs, that’s a potential problem both for physical reasons – and for psychological and developmental ones.
New York, like much of the country, was mired in a massive heat wave for much of this week. Everyone was complaining that they could hardly stand to go outside – the heat index was 100 degrees. Once high temperatures set in, I began feeling particularly faint and achy, like I was getting sick.
At first, I figured I was about to get a migraine, since I often feel like this before a particularly bad one. But no big headache arrived. Then I figured I was getting the flu. But I didn’t have other symptoms, like a sore throat or an upset stomach.
And then, I read an article online from the Philadelphia Inquirer about how heat and certain medications affect how well the body can regulate its own temperature, making people who take them more susceptible to extreme heat.
I knew that people who take lithium as a mood stabilizer have to be careful in the heat. The drug has has a narrow therapeutic range and can reach toxic levels in your system if you get dehydrated, something that’s much more likely to happen in hot weather.
But it was news to me that other psychiatric drugs, including the antidepressants I take, could alter the body’s ability to regulate its temperature.
In a recent post, I explored the question of whether meds can help reduce bullying behavior in kids with psychiatric conditions, since they are more likely to bully peers than kids without such problems.
But research shows that kids with psychiatric problems are also more likely to be bullied – and that those who are bullied are at elevated risk of suffering from psychiatric disorders later on.
In my own research for my book on young adults who grew up taking psychiatric meds, I was struck that almost everyone I interviewed reported having been bullied during childhood or adolescence (some also reported bullying other kids).
So how does taking psychiatric meds affect the likelihood of kids being bullied? Do the drugs enhance kids’ self-esteem and behavior so that they’re less likely to be picked on? Or do kids get teased because they take meds?
Last week, I featured a guest post from M., a reader from Texas who began taking Ritalin for ADHD when she was 12, then quit before college.
M. concluded in retrospect that taking that taking Ritalin taught her she couldn’t rely on herself to control her behavior. Instead, she learned to look to others for feedback, which she thinks provoked her anxiety.
Today, I’m following up with the second half of M.’s medication story, about her experience starting Zoloft in her mid-20s to treat some of that residual anxiety. Read on to find out how she fared during a second stab at medication treatment.
In this post, M., now 34 and living near Dallas, discusses how her views about Ritalin shifted as she got older. Ultimately, she came to suspect that relying on the medication actually exacerbated her anxiety – and may even have led, in a roundabout way, to her going on antidepressants later on.
And now, in her own words: