Psych Central

Causes Articles

NCAN Gene Linked to Mania

Thursday, September 20th, 2012

NCAN geneIn the September issue of the American Journal of Psychiatry, researchers report a series of studies that suggest a strong association between one particular genetic variation and manic symptoms. (Studies in humans and mice implicate neurocan in the etiology of mania. Miró X, Meier S, Dreisow ML, Frank J, Strohmaier J, Breuer R, Schmäl C, Albayram O, Pardo-Olmedilla MT, Mühleisen TW, Degenhardt FA, Mattheisen M, Reinhard I, Bilkei-Gorzo A, Cichon S, Seidenbecher C, Rietschel M, Nöthen MM, Zimmer A. Am J Psychiatry, 2012 Sep 1;169(9):982-90.)


Biological vs. Psychological Basis of Bipolar Disorder

Tuesday, July 12th, 2011

basis of bipolarA new report from the British Psychological Society entitled “Understanding Bipolar Disorder” suggests that viewing bipolar disorder solely as an illness with a biological basis may not be the most effective approach. The report seeks to re-establish a balance of biological and behavioral. Here’s a summary:

This report provides an overview of the current state of knowledge about why some people tend to experience periods of extreme mood and what can help. Much has been written about the biological aspects of bipolar disorders: this report aims to redress the balance by concentrating on the psychological aspects, both in terms of how we understand the problems and also approaches to help and treatment. We hope this report will influence the way in which services are delivered, so that more people have access to psychological treatments and that services will no longer insist that users accept one particular view of their problem.

Please check out the report and let us know what you think.

Added later: Although the report is free, you must register for a free account, login, add the report to your basket, and then proceed through the checkout process, but you won’t be prompted to enter a credit card number or anything like that.

After checking out, you’ll see a receipt showing that you’ve been charged nothing and providing a link you can click to download the report in PDF format. The report is 88 pages long.

Photo by DeepBluC, available under a Creative Commons attribution license.


Bipolar Disorder Q&A: Can Stimulants Trigger Mania?

Tuesday, September 7th, 2010

PMK asks…

My daughter Baker Acted eight days ago. She is 25 with no indication of a problem until a few weeks ago. She has ADD and was taking Adderall. She started taking Phentermine to lose weight and was taking energy drinks – Rock Star etc. She’s had a very demanding sales job in which she needed to go to networking events at night in addition to her job. She lost it this weekend while involved in a very stressful job-related event. It appears she lost her sense of reality – made many charges for clothes, stayed up almost with no sleep three or four days, said and did things out of character, until someone called 911.

Is it possible this was caused by all of these stimulants?


Bipolar Beat


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Candida Fink, M.D. and Joe Kraynak are authors of
Bipolar Disorder for Dummies.


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